Squirrel Patrol's Week 4 NFL DFS Tournament Strategy & Picks (DraftKings & FanDuel)

Sep 26, 2025
Squirrel Patrol's Week 4 NFL DFS Tournament Strategy & Picks (DraftKings & FanDuel)

Week 4 brings an 11-game main slate on Sunday, slightly trimmed from last week’s 13-game due to the Sunday morning game in Dublin and the Monday Night doubleheader. Both FanDuel and DraftKings have posted huge prize pools, including two Millionaire Maker tournaments on DraftKings.

Game totals are tightly bunched, with 10 of the 11 matchups sitting between 42.5 and 49.5 points. We see some large spreads, however, with Buffalo (-15.5) and Detroit (-10) both favored by double-digits. Injuries, particularly at quarterback and running back, continue to shape the DFS landscape.

Let’s break down the positions, spotlight some of the best DFS options, and map out a path to the top of the leaderboards this Sunday.

Quarterbacks

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