DraftKings & FanDuel NFL DFS Week 4 Cash Strategy & Picks

Sep 26, 2025

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Whether you are interested in turning $1 into $1.80 or $50 into $90, deploying a sound cash game strategy when you are building your lineup for Sunday main slates is crucial. Cash game fantasy grinders can run into pitfalls when they fail to recognize that the main goal of cash games is to maximize median and beat, often, a small group of opponents (or maybe just one) in the quest to do so.

Ceiling outcomes should be narrowly considered relative to maximizing your lineup’s projectable floor. You can save those high-upside strategies for the $1 million dollar to first-place contests on DraftKings or FanDuel, where you should focus on trading median for things like leverage, correlation, and low duplication. In cash games, there’s no reason to shy away from the player with 10x point-per-dollar value just because “everyone else is playing” him. If everyone else is playing him, it is probably a good indication that the market is aware of significant value.

4for4 has all the tools available to help you build your cash game lineups. This article is merely one of them. In the quest to grind out a solid edge (58%-62% win rates is very favorable), the most important tools at your disposal are mean projections, median projections, projection variance, point-per-dollar value, and a way to piece it all together (an advanced calculator is one option).

My goal for this weekly article is to consolidate all the crucial insights from our tools that can be used to gain an edge over your cash game opponents and help you put it all together to build lineups that have positive expected value.

Slate Context

Last week was a fun one for me in DFS. While it was certainly exciting, I’m just a little bit upset that I didn’t enter the lineup in the $5 single-entry double-up, where it would have returned an easy 100% ROI ($10) alongside the rest of the cash-game grinders. This week looks a bit tougher with a slightly smaller main slate and fewer obvious low- or minimum-salary options at the primary positions. Min-priced Mac Jones and Marcus Mariota are no longer options, but there’s still plenty of value on the board—and we’ll cover some of it here.

While obvious plays are less common this week, we can feel more confident in projection models and their ability to quantify what matters. As the season progresses, statistics and roles begin to normalize, helping us cut through surface-level box-score noise to identify true “signal” via opportunity and expectation informed by a larger sample. The deeper we get into the season, the more meaningful the numbers become—and the better they can guide our forward expectations.