Week 5 vs. New York Jets
Javonte Williams left Week 4 early and Samaje Perine still only saw eight touches. He only managed 35 total yards on those opportunities, and rookie Jaleel McLaughlin appeared to slot in as Williams' direct backup by seeing seven carries and three targets. McLaughlin looks like a real threat to Perine's contingent upside that was expected if Williams were to miss time, and the Broncos get a difficult matchup this week against the stout Jets defense. Perine will undoubtedly be involved in Week 5, perhaps more than usual if Williams is out, but the presence of McLaughlin makes him tough to stomach as a legitimate fantasy starter.