2022 NCAA Tournament: Sweet 16 Bets (Friday)

Mar 24, 2022

Jamie Sabau/NCAA Photos via Getty Images

This year's NCAA Tournament has given the public exactly what they want: Upsets early and Blue Bloods late.

The Sweet 16 certainly has its share of lower-seeded teams with No. 15 Saint Peter's, No. 11 Iowa State, and No. 10 Miami all crashing the party. However, the NCAA Tournament's second weekend also features historic programs such as Kansas, UCLA, and North Carolina.

Friday brings us four games spread over two sites (Philadelphia and Chicago). With one game (Miami vs. Iowa State) guaranteed to have a Cinderella team advance, will the other three top seeds hold serve?

Below are my betting predictions for Friday's fantastic Sweet 16 battles.

More 2022 NCAA Tournament: Schedule | Picks & Predictions | Futures Odds & Bets