NFL Week 1 Betting Picks: Against the Spread

Finally, Week 1 of the 2021 NFL season is almost here. We're about one week away from opening kickoff, but we're degenerates and can't contain ourselves from laying bets.

After studying the lines and key trends from across the NFL, I've found six games with spreads that are simply too attractive to not jump on. We'll have you covered throughout the 2021 NFL season with weekly spread picks as we look to profit all year long.

Week 1 NFL Betting Picks