I'm not sure who to start at flex position between Randall Cobb playing in Seattle or Joique Bell playing the Giants at home. If the Packers were at home I would probably go with Cobb. The Giants are not that good against the run.
I'd probably go with Cobb. I think that Lions-Giants game could put up some gaudy numbers, but Cobb is a stud, and the Seahawks will likely put Sherman on Nelson.