Calvin Johnson has sustained an ankle injury.
Johnson was leading Detroit with five catches for 85 yards when he left the game after suffering the injury while making a 30-yard catch in the fourth quarter of Sunday's game against the Kansas City Chiefs. He was characterized as doubtful to return.
Detroit was trailing 38-3 at the time of the injury.
Johnson has been relatively healthy this season, but did pop up on the injury report two weeks ago with an ankle, and received one day of veteran's rest this week while in London.
The good news is Johnson will have the bye week next Sunday to rest.