According to Staley, wide receiver Mike Williams, safety Nasir Adderley and cornerback Chris Harris Jr. will miss the pivotal game due to being on the reserve/COVID-19 list, per Fernando Ramirez of SI.

Related players: Jalen Guyton, Josh Palmer, Jason Moore

Williams was added to the list on Christmas, and due to the 10-day quarantine rule for unvaccinated players, he will miss Sunday. The NFL recently updated their protocols so that vaccinated players could "test out" of protocols more quickly. Since Adderley and Harris have already been ruled out, it would appear they are unvaccinated as well, according to the story. It's possible Guyton could test out and return. Moore caught three passes for 56 yards in Week 16.

Mike Williams and Austin Ekeler were limited Tuesday in practice.

Williams is dealing with a heel injury and Ekeler an ankle. Both are expected to play and with WR Keenan Allen off the COVID list the Bolts should be at full strength against the Chiefs on Thursday night in a huge AFC West battle.

Chargers WR Keenan Allen was activated off the COVID list.

Related players: Mike Williams, Jalen Guyton, Josh Palmer

Good news for the Bolts heading into a key AFC West game on Thursday night against the Chiefs. Williams didn't practice on Monday because of a heel issue, but the return of Allen likely downgrades Guyton and Palmer a bit for Week 15, assuming Williams plays as well.

Chargers WR Keenan Allen will miss Week 14's game against the New York Giants because of COVID-19 health and safety protocols.

Related Players: Mike Williams, Jalen Guyton, Josh Palmer

Williams is on the right track to play Week 14, which would go a long way to keep the Chargers from depending on two unproven wideouts.

Chargers WR Mike Williams has been placed on the reserve/COVID-19 list. He is deemed a close contact and is not officially ruled out for Week 14 yet.

Related Players: Jalen Guyton, Josh Palmer

Dire time in the Chargers receiver room. Pick up Guyton and/or Palmer as WR3/flex options this week.

Chargers HC Brandon Staley said WR Mike Williams’ knee isn’t why he’s had low numbers in the past four games.

Williams had one bad game on Oct. 4 but outside of that over the first five games he had six TDs and at least seven catches and 82 yards and a TD. That span included an 8-165-2 game vs. Cleveland and a 7-122-2 game vs. KC. Over the last four game he's totaled 10-137-0. “The knee is not an issue. It’s a non-factor," Staley said according to the tweet. Williams had knee swelling going into the Ravens game the tweet added. That was Oct. 17 - the beginning of his struggles over the last four games.

Chargers WR Mike Williams (knee) is questionable for Week 6 against the Baltimore Ravens.

Williams has been one of the best receivers in football this season. His loss would be one of the bigger ones assuming his misses. If Williams does, look for Jalen Guyton to get first crack at increased routes.

Los Angeles Chargers wide receiver Mike Williams was not spotted during the portion of practice open to the media.

Williams missed Wednesday's practice session with a knee injury, so the expectation is that he will be listed as DNP when the injury report is released later this evening. This is a new injury for Williams and is one that fantasy managers will want to monitor closely. Williams has finally started living up to his first round pedigree, so it would be a shame if an injury derailed his momentum (along with that of the Chargers as a whole). The Chargers veteran receiver is our ninth-ranked wideout for Week 6.

Los Angeles Chargers wide receiver Mike Williams is active for Thursday Night Football against the Las Vegas Raiders.

Mike Williams was hurt in the first quarter of Week 14’s win over Atlanta and was expected to miss Week 15 with the injury. However, the Chargers have elected kept him active for the divisional tilt against the Las Vegas Raiders. Williams may see his snaps limited due to the back issue, but will sap the upside from DFS darts Tyron Johnson and Jalen Guyton. Williams will be even more boom or bust than usual.