The information is scarce, but it seems like Mixon may have injured himself on Wednesday. Friday's official injury reports should give us a bit more to go on as far as Mixon's Week 11 status. In the meantime, make sure Giovani Bernard is owned in your league. If this ends up being something significant, Bernard would be an RB2 in Mixon's absence.
CIN RB Joe Mixon - Week 17 Fantasy Football Outlook
Week 17 at Pittsburgh Steelers
Joe Mixon's touches were down last week against Cleveland but don't let that bother you. The Bengals have been riding Mixon as their main offensive weapon since both Andy Dalton and AJ Green left the lineup. In the first meeting with the Steelers, Mixon had 15 touches for 84 yards and a touchdown.
Pittsburgh is ranked 13th in aFPA to running backs this season. We expect Mixon to be back around 20+ touches this week so start him as a low-end RB1 for Week 17.