49ers RB Matt Breida (ankle, doubtful) missed practice all week and is doubtful for Week 11. It appears that Matt Breida will miss 1-2 weeks with another ankle injury, and that means that Raheem Mostert and Jeff Wilson should each move up one spot in the 49ers' depth chart. With Tevin Coleman out Week 2 and Week 3, Mostert had 28 touches (3 catches) for 230 yards and a touchdown, so he's very much in the spot-start mix as a high-end RB3/flex. Wilson had FOUR rushing touchdowns in those two games, so he has multi-touchdown upside even though his yardage (52) wasn't much to write home about.
SF RB Jeff Wilson - Week 10 Fantasy Football Outlook
Week 10 vs. Seattle Seahawks
Jeff “The Vulture” Wilson stole four touchdowns over his first two games of the season, but he’s been largely inactive since. With Matt Breida and Tevin Coleman both expected to be active once again this week, there’s no reason to expect Wilson to get work. He may vulture a score again, but that’s super risky to count on and he should remain on waivers in all leagues.