Bills quarterback Trent Edwards was knocked out of the team's 16-13 overtime win over the New York Jets with a concussion following a sack early in the second quarter Sunday.
The Bills announced that Edwards had suffered a blow to the head, and coach Dick Jauron confirmed it was concussion after the game.
He was eventually taken to the locker room and Ryan Fitzpatrick replaced him on the Bills' next possession. Edwards was 5 of 5 for 43 yards before leaving.
Jauron said safety Donte Whitner left early with an injured ankle, defensive tackle Kyle Williams has an injured shoulder, cornerback Terrence McGee has a bruised chest and tight end Shawn Nelson suffered a concussion.