Lynch has not played in a game since Nov. 15, and he underwent abdominal surgery Nov. 25. He had been rehabbing in San Francisco but rejoined the team for workouts and practices this week.
But following the team's final workout at its practice facility Friday, the Seahawks said, Lynch notified them that he could not play Sunday. He did not travel with the team to Minneapolis later in the day.
According to a source, Lynch did not suffer any kind of setback with his injury during Friday's practice.
Over the past three games, Michael has seen 13.0 carries for 64 yards with a total of two catches for 14 yards. Brown has averaged 8.7 carries for 24 yards and scored a touchdown. In fact, he saw seven red zone touches over that span compared to just three for Michael. Fred Jackson led the Seattle running backs with eight catches for 66 yards over the three game span.