The Cardinals are placing RB James Conner (knee) on injured reserve, per source. He’s out at least four games.

Related players: Keaontay Ingram, Emari Demercado, Corey Clement, Tony Jones

As we reported all this week so far, any missed games from Conner could mean is Demercado Season. Ingram has missed the last couple of contests with his own injury, and when Conner went down last week, Demercado took over the lead role at running back - and even scored a touchdown. He's not necessarily a safe fantasy play, but in deeper leagues you may be able to at least count on his workload. The Cardinals travel to play the Rams which are among the better teams in rushing defense.

Cardinals’ RB James Conner is expected to miss multiple weeks with the knee injury he suffered Sunday vs. the Bengals.

Related players: Keaontay Ingram, Emari Demercado, Corey Clement, Tony Jones

Schefter went on to say Conner is now a candidate to be placed on injured reserve, per sources, which would mean he'll miss at least the next four games. After Conner left the game, Demercado took over the RB duties and will likely do so again with Conner out. Ingram is still dealing with a neck injury and has missed two-straight games and his status is unknown at this point for Week 6. The team did sign Jones but it looks like Demercado could be the RB1 at least in the short term. There's a very good chance Demercado is on your wire outside of deeper and dynasty leagues and could at least make for a usable fill-in at the running back spot.

Cardinals running back James Conner injured his knee in Sunday’s loss to the Bengals, playing only 12 snaps.

“I’m not quite sure yet, but it looks like [Conner could miss] a little bit of time,” Gannon told Arizona Sports on Monday. “We’re still working through that. James will be back at some point but honestly just wanted to add another back for some depth there to make sure we’re OK there for practice and for the games.”

Related players: Tony Jones, Emari Demercado, Keaontay Ingram, Corey Clement

The Cardinals added running back Tony Jones Jr. off waivers from the Saints, a sign Conner could miss time with his injury, the story pointed out. With Ingram (neck) also injured, Demercado replaced Conner and accounted for 57 scrimmage yards and a touchdown on 11 touches. Demercado could again be in line for more work if Conner has to miss time.

RB Marlon Mack is done for the season with an Achilles injury. Brutal injury for a guy who was here a few days.

Related Players: Keaontay Ingram, Corey Clement

Mack had a legitimate shot at earning the RB2 role in Arizona with a depth chart that is severely lacking. While Ingram could see more run in the short term, don't be surprised if the team is back on the hunt for a veteran presence.

On the Cardinals RB situation: James Conner is dealing with a rib issue, status will be clearer later in the week.

Related players: Darrel Williams, Eno Benjamin, Jonathan Ward, Corey Clement, Ty'Son Williams

The tweet went on to say Williams sprained his knee and is out this week and Ward is dealing with a hamstring injury and is on IR, per Tom Pelissero. The team recently signed Clement and Williams to the practice squad. One name not mentioned in terms of injuries is Benjamin, so if Conner is unable to go in Week 6, Benjamin would likely get a huge workload. Against the Eagles, Benjamin had eight carries and scored a TD while adding three catches. He's worth picking up if he's on your wire.

As Ravens open training camp this week, RB Gus Edwards (knee) is considered questionable for Week 1 (season opener at New York Jets).

Related players: J.K. Dobbins, Mike Davis, Corey Clement, Tyler Badie

There are a lot of questions around the Ravens RBs right now. Edwards is coming back from a torn ACL that he suffered in September and kept him out all of last season. The Ravens are hoping Dobbins (knee) will be back for the regular season. Baltimore signed Davis and Clement and drafted Badie. A lot will need to be sorted out before the regular season starts as far as the Baltimore backfield goes. Assuming their studs are healthy and ready to go, Baltimore is expected to be a run-heavy team in 2022.

Cowboys RB Tony Pollard (foot) did not travel with the team to Philadelphia and will not play Week 18.

Related Players: Ezekiel Elliott, Corey Clement

Pollard is a big loss for the Cowboys. Clement will take on a passing role with the Cowboys in Pollard's place.

Cowboys RB Tony Pollard (foot) is questionable for Week 15's game at the New York Giants.

Related Player: Corey Clement

Pollard got in two limited practices. If he does not play, Corey Clement will be Dallas's change-of-pace back.

Cowboys RB Tony Pollard rehabbed, but did not participate in practice Wednesday.

Related Player: Corey Clement

It would not be surprising to see Pollard out once again Week 15. Pick up Clement or have another option ready.

Cowboys coach Mike McCarthy is “feeling a lot better” about RB Tony Pollard’s ability to play Sunday.

Related players: Ezekiel Elliott, Corey Clement

The Cowboys take on the Giants and already say Pollard's chances are better now versus last week leading up to the game against Washington. Pollard missed his first game of season with a torn plantar fascia. It's worth nothing that Elliott and Clement split the workload, with Zeke getting 12 carries to Clement's 13 and each catching a pass as well.