Giants WR Hakeem Nicks (foot) has been downgraded to out and will not play vs. the Panthers. Nicks did not make the trip.
With Domenik Hixon also out, Ramses Barden should get first crack at snaps with rookie Rueben Randle not far behind. This has to be a downgrade for Eli Manning who will be without one of his biggest weapons. Martellus Bennett is also looking like a sneaky start.