In the Colts base offense, starting WRs were Reggie Wayne, Darrius Heyward-Bey.
The news here is T.Y. Hilton's value potentially takes a hit if this continues. This would make him the third option and the odd man out of the Colts' two-TE sets. It's early, of course, but it's something to monitor as he was considered a mid-round WR option. Obviously Heyward-Bey would move up the rankings as well.