Chargers rookie running back Ryan Mathews hurt his right ankle at the end of a 3-yard run in the first quarter of Sunday's 38-13 victory over Jacksonville and did not return.
Mathews had to be helped off the field. After being examined on the bench, Mathews was taken to the locker room on a cart. He jogged back to the bench midway through the second quarter.
Mathews was being tackled when Jaguars linebacker Kirk Morrison landed on his legs.
The extent of the injury is unknown at this time. The Chargers may well have simply kept Mathews from returning because the game was a blowout. Mike Tolbert received the majority of the early down work with Mathews out.