Seahawks linebacker Lofa Tatupu left Sunday's game against the Arizona Cardinals in the first half with a shoulder injury.
Minutes later, defensive end Patrick Kerney re-injured his groin.
Tatupu, a three-time Pro Bowler, appeared to get hurt while tackling Cardinals receiver Larry Fitzgerald late in the second quarter. Tatupu walked off holding his left chest area and with his left arm appearing limp.
Two team doctors and three trainers attended to him briefly on the bench. A doctor pressed on Tatupu's shoulder, and the linebacker reacted with a painful jerk.
A physician then escorted Tatupu into the locker room. The team announced his return was questionable. David Hawthorne was continuing to replace him in the third quarter.
That was when Seattle announced Kerney was out with a groin injury. The two-time Pro Bowler left the Seahawks' loss at Indianapolis on Oct. 4 with a strained groin, then missed last week's win over Jacksonville. He had two sacks of Kurt Warner and forced a fumble Sunday before he got hurt again. He watched the second half from the sideline.