Oakland Raiders running back Darren McFadden sat out his second consecutive practice with a sore hamstring and almost certainly will miss Sunday's game against the San Diego Chargers.
Michael Bush, off to a slow start after missing the first two games with a broken left thumb, handled the majority of reps in practice Thursday and likely will start against the Chargers.
McFadden's absence would be a blow to Oakland's sputtering offense. The former first-round draft pick is tied for third in the NFL with 392 rushing yards, 35 more than he had all last year. It's the best start by a Raiders running back since Lamont Jordan ran for 424 yards after four games in 2007.
The Raiders insist McFadden's injury isn't like the one that sidelined him early in training camp, but coach Tom Cable said it was "very, very doubtful" that the third-year pro would play Sunday.
Instead, Oakland will lean heavily on Bush, who has just 10 carries this season after leading the team in rushing in 2009.
Michael Bush is worth a pickup if you need someone to fill in, but the Raiders are going to have to keep this game close for Bush to get his carries.