Drew Stanton will make his first start of the season.
Palmer suffered a concussion on Sunday in a loss to the Los Angeles Rams. Coach Bruce Arians said Palmer made progress in recovery, but won't travel with the team out of precaution.
With Palmer out, Drew Stanton will get the start. In eight starts for the Cardinals in 2014, he averaged 203 passing yards with 0.75 touchdowns and 0.63 interceptions, so he doesn’t look like much of a streaming option even in a pretty good matchup with a mediocre San Francisco pass defense. Larry Fitzgerald, Michael Floyd and John Brown all take a hit in the rankings.